School of Bio-Chemical Engineering and Technology (BCET)
Dr. Wanwipa Siriwatwechakul
Assistant Professor
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+66-2-986-9009, +66-2-986-9101, +66-2-564-3226
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  • B.S. in Chemical Engineering, Massachusetts Institute of Technology, USA
  • M.S. in Chemical Engineering, Princeton University, USA
  • Ph.D. in Chemical Engineering, Princeton University, USA
  Academic Awards
  • King’s Scholarship, 1993.
  • Bronze Medal, International Chemistry Olympiad, 1992.
  Research Areas

Polymers and biomaterials.

  Research Interests

Polymer and Surfactant for Biomedical Applications
In conventional tissue engineering techniques, cells are grown on tissue culture polystyrene plates; these cells are then harvested by disaggregating the extracellular matrix (ECM) through the proteolytic action of trypsin or by chelating the Ca2+ and Mg2+ ions with ethylenediaminetetraacetic acid (EDTA). However, nonspecific proteases can damage crucial cell surface proteins, resulting in decline of cell function. A new technique using a temperature-responsive polymer grafted on a cell culture substrate has been investigated as an alternative. In the past few decades, poly(N-isopropylacrylamide) (PNIAM) has been extensively studied for this application. We are interested in developing a technique for grafting the copolymer of N-isopropylarylamide and acrylamide, poly(PNIAM-co-AM), onto commercial TCP surface using ultraviolet (UV) irradiation. It is a simple grafting technique without using expensive equipment, and it also provides more choices for tissue culture researchers who can choose a method that is compatible with their cell types and their facilities.

  Work Experiences
  • 2007- Present: SIIT
  • 2006-2007: Product Development Manager, B.M. Pharmacy LP. Bangkok, Thailand
  • 2005-2006: Consultant, ZS Associates, USA
  List of Publications
  • Sopita Wongin; Saranatra Waikakul; Pojchong Chotiyarnwong; Wanwipa Siriwatwechakul; Masahiro Kino-oka; Mee-Hae Kim; Kwanchanok Viravaidya-Pasuwat (2018). Maintenance of human chondrogenic phenotype on a dendrimer-immobilized surface for an application of cell sheet engineering, BMC Biotechnology, Vol. 18, 14 March 2018, Article No. 14, 11 p.
  • Sopita Wongin; Saranatra Waikakul; Pojchong Chotiyarnwong; Wanwipa Siriwatwechakul; Kwanchanok Viravaidya-Pasuwat (2018). Effect of cell sheet manipulation techniques on the expression of collagen type II and stress fiber formation in human chondrocyte sheets, Tissue Engineering Part A, Vol. 24, No. 5-6, March 2018, pp. 469-478.
  • Pham Le, Tu Phuong and Wanwipa Siriwatwechakul (2018). Applications of oxidized chitosan for scale prevention in sugar evaporators, Chiang Mai Journal of Science, Vol. 45, No. 2, March 2018, pp. 961-972.
  • Bui, Cuong Viet; Wanwipa Siriwatwechakul; Wareepat Tiyabhorn; Thammanont Wattanasiritham; Natthaphat Limpraditthanont; and Siwarutt Boonyarattanakalin (2016). Conversion of Jerusalem artichoke tuber powder into fructooligosaccharides, fructose, and glucose by a combination of microwave heating and HCl as a catalyst, Thammasat International Journal of Science and Techology, Vol. 21, No. 3, July-September 2016, pp. 31-45. 
  • Bui, Cuong Viet; Wanwipa Siriwatwechakul; Wareepat Tiyabhorn; Thammanont Wattanasiritham; Natthaphat Limpraditthanont; and Siwarutt Boonyarattanakalin (2016). Conversion of konjac powder into glucomannan-oligosaccharides, mannose, and glucose by hydrolysis facilitated by microwave heating and HCl catalyst, The Journal of Industrial Technology, Vol. 12, No. 2, May-August 2016, pp. 45-61.
  • Kanokaon Benchaprathanphorn; Pornprom Muangman; Phongphot Sakulaue; Wanwipa Siriwatwechakul; and Kwanchanok Viravaidya-Pasuwat (2015). Preparation and characterization of skin cell sheets for treatment of burn wounds. In Proceedings of the 2015 8th Biomedical Engineering International Conference (BMEiCON 2015), 25-27 November 2015, Pattaya City, Chonburi, Thailand, pp. 127-130.
  • Pham Le, Tu Phuong; and Wanwipa Siriwatwechakul (2015). Development of oxidized chitosan as an antiscalant in sugar processing. In Proceedings of the 2nd International Conference on Chemical Engineering, Food and Bio Technology (ICCFB2015), 30-31 October 2015, Ho Chi Minh City, Vietnam, pp. 153-157.
  • Swea, Aye Yu Yu; Kanokaon Benchaprathanphornb; Kwanchanok Viravaidya-Pasuwatb; and Wanwipa Siriwatwechakul (2015). Time study of UV grafting poly (N-isopropylacrylamideco-acrylamide) onto polystyrene surface for tissue culture engineering. In Proceedings of the 4th International Symposium on Engineering, Energy and Environment (ISEEE 4th), 8-10 November 2015, Pattaya City, Chonburi, Thailand, pp. 218-223.
  • Phongphot Sakulaue; Sopita Wong-In; Kwanchanok Viravaidya-Pasuwat; and Wanwipa Siriwatwechakul (2015). Modification and characterization poly (N-isopropylacrylamide-co-acrylamide) grafted tissue culture surface,International Proceedings of Chemical, Biological and Environmental Engineering: Proceedings of the 2015 4th International Conference on Informatics, Environment, Energy and Applications (IEEA 2015), 28-29 March 2015, Chonburi, Thailand, Vol. 82, pp. 15-19.
  • Charuwan Rojanathavorn; Chariya Paveenchana; Wuttipong Rungseesantivanon; and Wanwipa Siriwatwechakul (2014). Wood plastic composites (WPC) from ironwood (xylia xylocarpa) for wood floor applications. In Proceedings of the 2014 World Congress on Advances in Civil, Environmental, and Materials Research (ACEM’14), 24-28 August 2014, Busan, Korea, 12 p.
  • Kwanchanok Viravaidya-Pasuwat; Sopita Wong-in; Phongphot Sakulaue; and Wanwipa Siriwatwechakul (2013). Construction of a chondrocyte cell sheet using temperature-responsive poly(N-isopropylacrylamide)-co-acrylamide. InProceedings of the 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBC 2013) in conjunction with the 52nd Annual Conference of Japanese Society for Medical and Biological Engineering (JSMBE) [CD-ROM], 3-7 July 2013, Osaka, Japan, pp. 6969-6972.
  • Sopita Wong-In; Nguyen Thi KhanhThuyen; Wanwipa Siriwatwechakul; and Kwanchanok Viravaidya-Pasuwat (2013). Multilayered mouse preosteoblast MC3T3-E1 sheets harvested from temperature-responsive poly(N-isopropylacrylamide-co-acrylamide) grafted culture surface for cell sheet engineering, Journal of Applied Polymer Science, Vol. 129, No. 5, 5 September 2013, pp. 3061-3069.
  • W. Siriwatwechakul; J. Siramanont; and W. Vichit-Vadakan (2012). Ion filtration effect of superabsorbent polymers for internal curing. In Proceedings of the Twelfth International Conference on Recent Advances in Concrete Technology and Sustainability Issues, 30 October – 1 November 2012, Czech Republic, pp. 389-397.
  • W. Siriwatwechakul; J. Siramanont; and W. Vichit-Vadakan (2012). Behavior of superabsorbent polymers in calcium- and sodium-rich solutions, Journal of Materials in Civil Engineering, Vol. 24, No. 8, August 2012, pp. 976-980.
  • Bhornpan Pipatpongkul and Wanwipa Siriwatwechakul (2010). Economic evaluation of the recombinant human erythropoietin (rhEPO) production process. In Proceedings of the 17th Regional Symposium on Chemical Engineering (RSCE 2010), 22-23 November 2010, Bangkok, Thailand. 6 p.
  • Wanwipa Siriwatwechakul; Jirawan Siramanont; and Wilasa Vichit-Vadakan (2010). Superabsorbent polymer structures. In Proceedings of the International RILEM Conference on Use of Superabsorbent Polymers and Other New Additives in Concrete, 15-18 August 2010, Lyngby, Denmark. pp. 253-262.
  • Nunnarpas Yongvongsoontorn and Wanwipa Siriwatwechakul (2009). Microspheres of poly(acrylamide) hydrogels with semiinterpenetrating networks of poly(N-isopropylacrylamide). In Proceedings of the 4th International Symposium on Biomedical Engineering (IEEE ISBME 2009) [CD-ROM], 14-18 December 2009, Bangkok, Thailand. 4 p.
  • Wanwipa Siriwatwechakul (2009). Temperature-sensitive polyacrylamide hydrogels. In Proceedings of the 2nd Thammasat University International Conference on Chemical, Environmental and Energy Engineering (TU ChEEE 2009) [CD-ROM], 3-4 March 2009, Bangkok, Thailand. pp. 232.237.
  • Wilairat Supmak; Atitsa Petchsuk; Pakorn Opaprakasit; Alice Sharp; and Wanwipa Siriwatwechakul (2009). Synthesis and characterizations of copolymers of lactide and glycidyl methacrylate: effects of synthesis conditions. InProceedings of the 2nd International Conference on Green and Sustainable Innovation (ICGSI 2009) [CD-ROM], 2-4 December 2009, Chiang Rai, Thailand. 7 p.
  • Wanwipa Siriwatwechakul; Nutte Teraphongphom; Vatcharani Ngaotheppitak; and Sureeporn Kunataned (2008). Thermo-sensitive hydrogel: control of hydrophilic-hydrophobic transition. In Proceedings of World Academy of Science, Engineering and Technology, 4-6 July 2008, Paris, France. Vol. 30, pp. 1046-1051.