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BIOMEDICAL ENGINEERING RESEARCH UNIT (BIOMED)
Announcement
Doctoral Degree Scholarship with the Biomedical Engineering Research Unit combined with SIIT scholarship for Excellent Foreign Students or SIIT scholarship for Excellent Thai Students: free tuition and up to 30,000 Baht (approx. $1,000) per month allowance (conditions apply).
Download Biomed brochure (English Version)
Download Biomed brochure (Thai Version)

Double Degree Doctoral Program in Biomedical Engineering:  SIIT/ Chiba University of Japan (DDDP)
The DDDP must be combined with EFS/ETS for doctoral students with excellent academic records. It offers 100% education and tuition fees, thesis support, living allowance, airfare, health insurance and other benefits. The program is expected to obtain additional financial support from Thailand government agencies.
Download DDDP brochure

Contact
Prof. Stanislav Makhanov
makhanov@siit.tu.ac.th

Introduction
Biomedical Engineering unit (BioMed SIIT) integrates fundamentals from engineering, computer science, medical science and mathematics to solve applied problems in medicine and biology. Our expertise related to BioInformatics and Biomedical Engineering, Optimization and Numerical Analysis ranges from medical image analysis to producing medical implants and CNC programming.

The BioMed offers scholarships for prospective PhD students.

Websites  
  Prof. Dr. Stanislav Makhanov
(Unit Head)
medical image processing , CNC machining of medical implants
  Prof. Dr. Siriwan Suebnukarn
(Department of Dentistry, TU)
dentistry, virtual reality
  Assoc. Prof. Dr. Waree Kongprawechnon
control engineering
  Assoc. Prof. Dr. Bunyarit Uyyanonvara
medical image processing, retinal image analysis
  Assoc. Prof. Dr. Toshiaki Kondo
medical image processing
  Assoc. Prof. Dr. Utairat Chaumrattanakul
(Department of Radiology, TU)
radiology
  Asst. Prof. Dr. Pakinee Aimmanee
medical image processing
  Asst. Prof. Dr. Itthisek Nilkhamhang
control engineering, robotics
     

Objectives

The main objectives of the BioMed are to develop reliable and practical applications in the biomedical engineering, produce joint research papers, conduct an efficient collaborative supervision of graduate students and arrange for cooperation with other faculties of TU and other research groups and universities in the country. The unit attracts computer science experts working in the field of biomedical applications and researchers working in practical medicine to find common grounds and joint applications. Usually, such units are organized and run by medical experts who invite computer scientists to computerize their solutions or computer scientists who want to run their algorithms on real world examples. The idea of this unit is different: the computer scientists and medical experts offer their vision collaboratively, producing interdisciplinary research.The unit is focused on
  1. Obtaining research funding and support from national and international funding agencies.
  2. Consolidating biomedical research within SIIT and TU by collaborative interactive efforts among researchers with complementary backgrounds, skills, and expertise.
  3. Publishing high quality research papers in top international journals.
  4. Helping young faculty members to start up and develop academic research and applications.
  5. Organizing international research conferences and workshop.
  6. Organizing training courses and research seminars.
  7. Finding sponsorships to award the best student research works in this area.
  8. Providing PhD and postdoc scholarships in biomedical engineering
The long term objectives include
  1. Educational programs in collaboration with other schools such as the school of Dentistry of Thammasat University, or the Department of Radiology. The Master or Ph.D. program aimed at particular aspects of Biomedical Engineering and possibly sponsored by the industry serves this idea.
  2. Developing solid self supporting research groups dedicated to particular aspects of Bioengineering or Biomechanics.

Scope of Research
  • Medical image processing and analysis
  • Bioinformatics
  • Biomedical engineering
  • Medical implants and CNC programming
  • Biomedical instrumentation
  • Smart prosthetics design
  • Optimization and numerical analysis

Current Sponsored Research Projects
  • Diabetic Retinopathy Screening System
  • About 6,000,000 people need to have their eyes scanned for diabetic retinopathy each year. Thailand’s total of 800 ophthalmologists is clearly outnumbered. The project offers an automatic computerized image processing system to help the doctors to screen the patients (National Research University Project) .
  • Diagnostic of Breast Cancer: Continuous Force Field Analysis for Ultrasound Image Segmentation
  • The project offers a new approach to segmentation of ultrasound images of the breast tumors based on the active contour method combined with a new force field analysis techniques The project will make it possible to extend these ideas to a variety of practical examples of the breast or liver tumor segmentations from noisy images and to the cases when the contour is initialized far from the boundary (Thailand Research Fund).
  • Five-Axis Computer Aided Manufacturing of Dental Implants
  • The project aims to create an easy to use and inexpensive system for producing dental crowns using multi axis milling machines. The methods will be adapted to the specific demands of dental machining. The optimization makes it possible to produce the crowns faster and more accurate as compared to conventional rapid prototyping and general purpose CAD/CAM systems or DentMill, CEREC, etc (National Research University Project) .
  • A real-time motion estimation technique using unit gradient vectors (Thammasat University).
  • Automated retinal image analysis for glaucoma detection (Thammasat University).

External Members
  • Dr. Annupan Rodtook, Ramkhampang University , Medical Pattern Recognition
  • Ir. Erik Bohez, Asian Institute of Technology, CAD/CAM CNC
  • Dr. Sarah Barman, Kingston University, Medical Image Processing
  • Dr. Chanjira Sinthanayothin, NECTEC, Image Processing
  • Dr. Sirikan Chucherd, Medical Image Processing, Me Fah Luang University

Partners
  • Thammasat University, Department of Radiology
  • Thammasat University, Department of Dentistry
  • Kingston University, UK
  • Asian Institute of Technology
  • National Institute of Metrology of Thailand

Selected Publications
  1. Keatmanee, C., Makhanov, S.S., Kotani, K., Kondo, T., and Thongvigitmanee, S.S.(2015). Inferior alveolar canal segmentation in cone beam computed tomography images using an adaptive diffusion flow active contour model, Proceedings of the 14th IAPR International Conference on Machine Vision Applications, MVA 2015, Art. No. 7153132, pp. 57-60.
  2. Moodleah, S., and Makhanov, S.S. (2015). 5-axis machining using a curvilinear tool path aligned with the direction of the maximum removal rate, International Journal of Advanced Manufacturing Technology, Vol. 80, No. 1-4, pp. 65-90.
  3. Muangnak, N., Aimmanee, P., Makhanov, S., and Uyyanonvara, B.(2015). Vessel transform for automatic optic disk detection in retinal images, IET Image Processing, Vol. 9, No. 9, pp. 743-750.
  4. Srijuntongsiri, G., Makhanov, S.S. (2015). Optimisation of five-axis machining G-codes in the angular space, International Journal of Production Research, Vol. 53, No. 11, pp. 3207-3227.
  5. Vanderperre, E.J., and Makhanov, S.S. (2015). Reliability of Birolini’s duplex system sustained by a cold standby unit and subjected to a priority rule, TOP, Vol. 23, No. 2, pp. 441-465.
  6. Clangphukhieo, B., Aimmanee, P., and Uyyanonvara, B. (2014). Segmenting the ventricle from CT brain image using Gray-level Co-occurrence Matrices (GLCMs), Lecture Notes in Engineering and Computer Science, Vol. 1, pp. 585-589.
  7. Japunya, T., Jitpakdee, P., Uyyanonvara, B., Aimmanee, P., Philippaki, E., Hull, C., and Barman, S. (2014). Software for the quantification of glistenings in intra-ocular lenses, Lecture Notes in Engineering and Computer Science, Vol. 1, pp. 34-38.
  8. Thanathornwong, B., Suebnukarn, S., Songpaisan, Y., and Ouivirach, K. (2014). A system for predicting and preventing work-related musculoskeletal disorders among dentists, Computer Methods in Biomechanics and Biomedical Engineering, Vol. 17 No. 2, pp. 177-185.
  9. Turior, R., Uyyanonvara, B., and Chutinantvarodom, P. (2014). Automatic evaluation of plus disease in retinopathy of prematurity, Applied Mechanics and Materials, Vol. 530-531, pp. 189-196.
  10. Turior, R., and Uyyanonvara, B. (2014). Comparative analysis of automatic tortuosity classification algorithms, WIT Transactions on Information and Communication Technologies, Vol. 58 VOL I, pp. 309-317.
  11. Ekkachai, K., Tungpimolrut, K. and Nilkhamhang, I. (2013). Force control of a magnetorheological damper using an elementary hysteresis model-based feedforward neural network, Smart Materials and Structures, Vol. 22, No. 11, November 2013.
  12. Kazi, H., Haddawy, P., and Suebnukarn, S. (2013). Clinical reasoning gains in medical PBL: An UMLS based tutoring system, Journal of Intelligent Information Systems, Vol. 41, No. 2, pp. 269-284.
  13. Rodtook, A. and Makhanov, S.S. (2013). Multi-Feature Gradient Vector Flow Snakes f or Adaptive Segmentation of the Ultrasound Images of Breast Cancer, Journal of Visual Communication and Image Representation, Vol. 24, No. 8, November 2013, pp. 1414-1430.
  14. Sopharak, A., Uyyanonvara, B., and Barman, S. (2013). Simple hybrid method for fine microaneurysm detection from non-dilated diabetic retinopathy retinal images, Computerized Medical Imaging and Graphics, Vol. 37, No. 5-6, pp. 394-402.
  15. Turior, R., Chutinantvarodom, P., and Uyyanonvara, B. (2013). Automatic tortuosity classification using machine learning approach, Applied Mechanics and Materials, Vol. 241-244, pp. 3143-3147.
  16. Turior, R., Onkaew, D., and Uyyanonvara, B. (2013). PCA-based retinal vessel tortuosity quantification, IEICE Transactions on Information and Systems, Vol. E96-D, No. 2, February 2013, pp. 329-339.
  17. Turior, R., Chutinantvarodom, P., and Uyyanonvara, B. (2013). Semi-automated computer analysis of retinal vessels in premature infants, Applied Mechanics and Materials, Vol. 241-244, pp. 2962-2968.
  18. Fraz, M.M., Barman, S.A., Remagnino, P., Hoppe, A., Basit, A., Uyyanonvara, B., Rudnicka, A.R. and Owen, C.G. (2012). An approach to localize the retinal blood vessels using bit planes and centerline detection, Computer Methods and Programs in Biomedicine, Vol. 108, No. 2, November 2012, pp. 600-616.
  19. Fraz, M.M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Rudnicka, A.R., Owen, C.G. and Barman, S.A. (2012). Blood vessel segmentation methodologies in retinal images - A survey, Computer Methods and Programs in Biomedicine, Vol. 108, No. 1, October 2012, pp. 407-433.
  20. Fraz, M.M., Barman, S.A., Remagnino, P., Hoppe, A., Basit, A., Uyyanonvara, B., Rudnicka, A.R. and Owen, C.G. (2012). An approach to localize the retinal blood vessels using bit planes and centerline detection, Computer Methods and Programs in Biomedicine, Vol. 108, No. 2 , pp. 600-616.
  21. Fraz, M.M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Rudnicka, A.R., Owen, C.G., and Barman, S.A. (2012). An ensemble classification-based approach applied to retinal blood vessel segmentation, IEEE Transactions on Biomedical Engineering, Vol. 59, No. 9, pp. 2538-2548.
  22. Kazi, H., Haddawy, P., and Suebnukarn, S. (2012). Employing UMLS for generating hints in a tutoring system for medical problem-based learning, Journal of Biomedical Informatics, Vol. 45, No. 3, pp. 557-565.
  23. Suebnukarn, S., Rhienmora, P., and Haddawy, P. (2012). The use of cone-beam computed tomography and virtual reality simulation for pre-surgical practice in endodontic microsurgery, International Endodontic Journal, Vol. 45 No. 7, pp. 627-632.
  24. Anotaipaiboon, W. and Makhanov, S.S. (2011). Minimization of the kinematics error for five-axis machining, Computer-Aided Design, Vol. 43, No. 12, December 2011, pp. 1740-1757.
  25. Fraz, M.M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Owen, C.G., Rudnicka, A.R. and Barman, S. (2011). Retinal Vessel Extraction Using First-Order Derivative of Gaussian and Morphological Processing. In proceeding of: Advances in Visual Computing - 7th International Symposium, ISVC 2011, Vol. 1, September 26-28, 2011, Las Vegas, NV, USA, pp. 410-420.
  26. Sopharak, A., Uyyanonvara, B. and Barman, S. (2011). Automatic Microaneurysm Detection from Non-dilated Diabetic Retinopathy Retinal Images Using Mathematical Morphology Methods, IAENG International Journal of Computer Science, Vol. 38, No. 3, August 2011, pp. 295-301.
  27. Duanggate, C., Uyyanonvara, B., Makhanov, S.S., Barman, S., and Williamson, T. (2011). Object Detection with Feature Stability over Scale Space, Journal of Visual Communication and Image Representation, Vol. 22, No. 4, May 2011, pp. 345-352.
  28. Duanggate, C., Uyyanonvara, B., Makhanov, S.S., Barman, S. and Williamson, T. (2011). Parameter-free optic disc detection, Computerized Medical Imaging and Graphics, Vol. 35, No. 1, January 2011, pp. 51-63.
  29. Yuenyong, S., Nishihara, A., Kongprawechnon, W. and Tungpimolrut, K. (2011). A framework for automatic heart sound analysis without segmentation, BioMedical Engineering Online, Vol. 10.
  30. Duanggate, C., Uyyanonvara, B., Makhanov, S.S., Barman, S. and Williamson, T. (2011). Parameter-free optic disc detection, Computerized Medical Imaging and Graphics, Vol. 35, No. 1, pp. 51-63.
  31. Sopharak, A., Uyyanonvara, B. and Barman, S. (2011). Automatic microaneurysm detection from non-dilated diabetic retinopathy retinal images using mathematical morphology methods, IAENG International Journal of Computer Science, Vol. 38, No. 3, pp. 295-301.
  32. Duanggate, C., Uyyanonvara, B., Makhanov, S.S., Barman, S. and Williamson, T. (2011). Object detection with feature stability over scale space, Journal of Visual Communication and Image Representation, Vol. 22, No. 4, pp. 345-352.
  33. Boonsieng, P., Kondo, T. and Kongprawechnon, W. (2011). Unit gradient vectors based motion estimation techniques, Transactions on Electrical Engineering, Electronics, and Communications, Vol. 9, No. 2, pp. 246-254.
  34. Nakaguro, Y., Makhanov, S.S. and Dailey, M.N. (2011). Numerical experiments with cooperating multiple quadratic snakes for road extraction, International Journal of Geographical Information Science, Vol. 25, No. 5, pp. 765-783.
  35. Rhienmora, P., Haddawy, P., Suebnukarn, S., and Dailey, M.N. (2011). Intelligent dental training simulator with objective skill assessment and feedback, Artificial Intelligence in Medicine, Vol. 52, No. 2, pp. 115-121.
  36. Inglam, S., Suebnukarn, S., Tharanon, W., Apatananon, T., Sitthiseripratip, K. (2010). Influence of graft quality and marginal bone loss on implants placed in maxillary grafted sinus: a finite element study, Medical and Biological Engineering and Computing, Vol. 48, No. 7, pp. 681-689.
  37. Rhienmora, P., Haddawy, P., Khanal, P., Suebnukarn, S., and Dailey, M.N. (2010). A virtual reality simulator for teaching and evaluating dental procedures, Methods of Information in Medicine, Vol. 49, No. 4, pp. 396-405.
  38. Rodtook, A., and Makhanov, S.S. (2010). Continuous force field analysis for generalized gradient vector flow field, Pattern Recognition, Vol. 43, No. 10, October 2010, pp. 3522-3538.
  39. Sopharak, A., Dailey, M.N., Uyyanonvara, B., Barman, S., Williamson, T., Nwe, K.T. and Moe, Y.A. (2010). Machine Learning Approach to Automatic Exudate Detection in Retinal Images from Diabetic Patients, Journal of Modern Optics, Vol. 57, No, 2, January 2010, pp. 124 – 135.
  40. Sopharak, A., Dailey, M.N., Uyyanonvara, B., Barman, S., Williamson, T., Nwe, K.T. and Moe, Y.A (2010). Machine learning approach to automatic exudate detection in retinal images from diabetic patients, Journal of Modern Optics, Vol. 57, No. 2 , pp. 124-135.
  41. Suebnukarn, S., Haddawy, P., Rhienmora, P., Jittimanee, P., and Viratket, P. (2010). Augmented kinematic feedback from haptic virtual reality for dental skill acquisition, Journal of Dental Education, Vol. 74, No. 12, pp. 1357-1366.
  42. Sopharak, A., Uyyanonvara, B., Barman, S. and Williamson, T. (2009). Comparative analysis of automatic exudate detection between machine learning and traditional approaches, IEICE Transactions on Information and Systems, Vol. E92-D, No. 11, pp. 2264-2271.
  43. Sopharak, A., Uyyanonvara, B. and Barman, S. (2009). Automatic exudate detection from non-dilated diabetic retinopathy retinal images using Fuzzy C-means clustering, Sensors, Vol. 9, No. 3, pp. 2148-2161.
  44. Sukkaew, L., Uyyanonvara, B., Makhanov, S.S., Barman, S. and Pangputhipong, P. (2008). Automatic tortuosity-based retinopathy of prematurity screening, IEICE Transactions on Information and Systems, Vol. E91-D, No. 12, December 2008, pp. 2868-2874.

PhD graduates
  1. Dr. Annupan Rodtook : Adaptive Noise Removal and Wavelet Moments for 2D Pattern Recognition.
  2. Dr. Sirikan Chucherd: Phase Portrait Analysis for Generalized Gradient Vector Flow Applied to Segmentation of Ultrasound Images of Breast cancer
  3. Dr. Weerachai Anotaipaiboon: New Algorithms for Tool Path Generation and Optimization for Five-Axis Milling Machines.
  4. Dr. Akara Sopharak: Automatic Detection of Diabetic Retinopathy from Digital Retinal Images.
  5. Dr. Cattleya Duanggate: Variable Component Detection with the Scale Space Theory
Ph.D. students
  1. Yoichi Nakaguru, Snakes for Segmentation of Complex Objects.
  2. Samart Moodleah, 5 Axis Machining to Produce Medical Implants
  3. Khwunta Kirimasthong, Ultrasound Image Processing
  4. Ms. Rashmi Turior, Automatic Tortuosity measurement
  5. Ms. Chadaporn Keatmanee, 3D active contours
  6. Ms. Nittaya Muangnak, Retinal Image Processing
  7. Ms. Parisut Jitpakdee, Retinal Image Processing
  8. Mr. Kittipong Ekkachai, Smart Prosthetic Knee Design with Variable Damping Control using Magneto-rheological Dampers
  9. Mr. Pramuk Boonsieng. Optical Flow Estimation in Video Sequences with Application to Medical Imaging
  10. Suthum Keerativittayanun, Generation of a High-dynamic Range Images with Application to Medical Image Processing
Completed Sponsored Research Projects
  1. Optimization of the tool path of 5 axis milling machines (National Electronics and Computer Technology Center).
  2. New methods for optimization of the tool path of 5 axis milling machines (Thailand Research Fund)
  3. Snakes for breast cancer detection (Thailand Research Fund ).
  4. Diabetic Retinopathy Screening System (National Electronics and Computer Technology Center ).
  5. Feasibility study of angle-closure glaucoma screening device ( National Science and Technology Development Agency).
  6. Development of an eye tracking system for ophthalmic diagnosis (National Science and Technology Development Agency).
  7. Automatic gesture recognition in real image sequences (Thammasat University)
Contact
Prof. Dr. Stanislav Makhanov
Biomedical Engineering Research Unit
Sirindhorn International Institute of Technology (SIIT),
Thammasat University, Pathum Thani, 12121, Thailand
Tel: +66-2-501-3505~20 ext 5001
Email: makhanov@siit.tu.ac.th